Can You Take Supplements with HRT?

← Back to Learn · By Kathryn Carter · Last updated: 26 August 2026

Short answer: often yes, but not automatically — it depends on the supplement, not on HRT as a category. The rule that never fails: bring the full ingredient list to your GP or pharmacist and ask. This page explains what they'll be looking for, so the conversation is a quick one.

Why "it depends on the supplement"

Menopausal hormone therapy (MHT/HRT) delivers oestrogen, usually with a progestogen. The question for any supplement alongside it is whether an ingredient might affect hormones itself, or affect how your body processes medicines. Most nutrients don't. Some herbs can. That's the entire logic — everything else is detail.

The ingredients worth asking about

• Vitex (chaste tree) — found in many hormonal-support formulas, including our Hormone Balance Plus. Our label says it plainly: Vitex may affect hormones and medicines such as oral contraceptives. If you're on HRT or hormonal contraception, this is a talk-to-your-GP-first ingredient — not a never, a check-first.
• St John's Wort — not in any MyPause product, but worth knowing as the classic example: it speeds up the breakdown of many medicines and is a well-documented interaction risk. If a "mood support" formula contains it, ask your pharmacist before combining it with anything.
• Herbal sedatives (valerian, hops) — as in our Sleep Assist. The consideration here isn't HRT specifically — it's other sedating medicines. Tell your pharmacist everything you take.
• High-dose anything — doses matter, which is why we publish ours and why undisclosed "proprietary blends" make this conversation impossible.

The lower-drama category: food-based nutrition

Products that are foods rather than medicines — protein, creatine, fibre, electrolytes — sit in a different category from herbal medicines. They're nutrition, not pharmacology. Your GP should still know your full routine (fibre supplements, for instance, are best taken a couple of hours away from oral medicines so absorption isn't affected), but these are generally short conversations.

How to have the five-minute conversation

1. Screenshot or list every supplement you take — ingredient names and doses, not just brand names. (Every MyPause product page has the full panel; that's deliberate.)
2. Ask two questions: "anything here that interacts with my HRT or other medicines?" and "anything here I'm doubling up on?"
3. Pharmacists are excellent for this and don't need an appointment.

What we won't tell you

We won't tell you our products are "safe with HRT" as a blanket statement — nobody selling supplements should, because they haven't met you, your medicines or your history. What we can do is publish every ingredient and dose, print the interaction warnings in plain language, and make your GP's job easy. That's the deal.

Common questions

Can I take Hormone Balance Plus with HRT?

Check with your GP or pharmacist first — it contains Vitex, which may affect hormones and medicines such as oral contraceptives. Bring the ingredient list from the product page; it's a quick conversation.

Can I take creatine or protein with HRT?

Creatine and protein are foods rather than herbal medicines, so they sit in a lower-drama category — but your GP or pharmacist should still know your full routine. See our guide to creatine for women over 40.

Should I stop supplements before starting HRT?

Don't stop or start anything based on a website — ours included. Take your full supplement list to the appointment where HRT is being discussed, and decide together. That's genuinely the best-practice answer.

This page is general information, not medical advice. Always read the label and follow the directions for use. If symptoms persist, talk to your health professional.

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